The ARYx mission is to make proven therapies safer. By applying its retrometabolic approach to pharmaceutical discovery and development, ARYx serves patients by fundamentally improving the safety of oral therapies in large, chronic markets while maintaining their efficacy. To optimize shareholder value, ARYx’s strategy was to become a profitable company with a continuing pipeline of products, balancing risk against rewards through collaborations with pharmaceutical partners. In November 2007 the company completed an initial public offering led by Morgan Stanley and trades under the NASDAQ symbol ARYX.

Lifeline Technologies is a health sciences development company focused on novel strategies for lowering human cholesterol absorption by using plant sterols and stanols to block the absorption of free cholesterol in the small intestine. The company is using licensed patented intellectual property from Washington University, St. Louis, to develop complementary approaches in the following three areas: dietary supplements, food ingredients and pharmaceuticals. The company has ready access to an enabling clinical technology for the measurement of human cholesterol absorption that permits rapid assessment of promising cholesterol lowering candidates and dosing regimens. Lifeline has entered into a licensing arrangement with Archer Daniels Midland Company for worldwide food and beverage applications.

Alacritech is a Silicon Valley company which pioneered the use of “intelligent” network interface cards to offload TCP/IP processing from the CPU of computer systems to dedicated hardware on the NIC: a concept now known as TOE.

Alacritech continues to license its patented accelerator technology, but is no longer manufacturing the ANX series of NFS accelerators. ANX customers will continue to receive strong support through a special team which has been put in place to assure that support contracts are fully met.

Callixa specialized in helping overcome the critical challenge of data access and integration in enterprises running multiple, disparate databases. Callixa provided the first enterprise platform capable of creating a standard access layer for writing and reading data to and from all data sources of an enterprise. Callixa’s solutions and services allowed companies to rapidly build business applications without the time and expense of developing and maintaining customized data integration access for each application.

Layer 7 Technologies helped enterprises secure and govern interactions between their organizations and the services they use in the cloud; across the internet; and out to mobile devices.

Through its award-winning line of SOA Gateways, Cloud Brokers and API Proxies, Layer 7 gave enterprises the ability to control identity, data security, SLA and visibility requirements for sharing application data and functionality across organizational boundaries. In 2011, Layer 7 was named the 71st fastest-growing private or public technology company in North America on the Deloitte Fast 500 list. With more than 150 customers spanning six continents, Layer 7 supported the most demanding commercial and government organizations. Layer 7 solutions are FIPS compliant, STIG vulnerability tested and have met Common Criteria EAL4+ security assurance.

Strutta’s platform allows brands, small business and non-profits to build contests, sweepstakes and other products in order to help them connect with and grow their audience across multiple social web channels.  The social management dashboard allows brands to better understand how their participants are engaging with their brand and sharing their experiences.

Boreal has developed a revolutionary new approach for analysis of circulating tumor DNA in plasma enabling real-time monitoring of disease progression.   Applications include therapy selection, monitoring, and early detection of disease. Boreal’s OnTarget™ technology selectively enriches the sample for targeted DNA sequences to reveal tumor mutations which help guide clinical decision making and improve clinical trials or drug development programs.

Copperleaf is a leading provider of decision analytics solutions for organizations facing the challenges of aging infrastructure.  The technology leverages operational and financial data to empower these organizations to make the highest value investment decisions. Copperleaf C55 is a unique Asset Investment Planning & Management (AIPM) solution that helps customers make risk-informed decisions that are effective, transparent and focused on long-term performance.